6-Bromoisoquinoline → HCID 58416489, compound

HRID 1015083Notes

Reaction equation

Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[N:7][CH:6]=[CH:5]2.C[Sn](C)(C)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=1.[BH4-].[Na+]>>[N:15]1[CH:16]=[CH:17][CH:18]=[CH:19][C:14]=1[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH2:8][NH:7][CH2:6][CH2:5]2

Participants

Reactant 3

HCID 3136816-Bromoisoquinoline

HCID 4311764Sodium borohydride

HCID 11021057Pyridine, 2-(trimethylstannyl)-

Product 1

HCID 58416489HCID 58416489, compound

Procedure

In close analogy to the procedure described above, 6-Bromo-isoquinoline is reacted with 2-trimethylstannyl-pyridine and sodium borohydride to provide the title compound.

Sources & evidence

ORD record: ord-c5a9b7d87c1c44d78be3c8855640ab75
Source dataset: uspto-grants-2011_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07985753B2

Reaction notes

Loading…