HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine → (3-Bromo-7,8-dihydro-5H-[1,6]naphthyridin-6-yl)-(6-chloro-pyrazolo[1,5-a]pyrimidin-2-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-5,6,7,8-tetrahydro-1,6-naphthyridine | HCID 17750398 | — |
| Reactant | 6-Chloropyrazolo[1,5-A]pyrimidine-2-carboxylic acid | HCID 33695678 | — |
| Product | (3-Bromo-7,8-dihydro-5H-[1,6]naphthyridin-6-yl)-(6-chloro-pyrazolo[1,5-a]pyrimidin-2-yl)-methanone | HCID 24810736 | 66% |
Reaction Steps
In close analogy to the procedure described in Example 1, 6-chloro-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is reacted with 3-Bromo-5,6,7,8-tetrahydro-[1,6]naphthyridine to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07985753B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-cb617318b52442fabdb593fdf679b2e1 |
| Source note | uspto-grants-2011_07 |