HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloropyrazolo[1,5-A]pyrimidine-2-carboxylic acid → (6-Chloro-pyrazolo[1,5-a]pyrimidin-2-yl)-(1-methyl-7-pyridin-2-yl-3,4-dihydro-1H-isoquinolin-2-yl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloropyrazolo[1,5-A]pyrimidine-2-carboxylic acid | HCID 33695678 | — |
| Reactant | 1-Methyl-7-pyridin-2-yl-1,2,3,4-tetrahydro-isoquinoline | HCID 58416309 | — |
| Product | (6-Chloro-pyrazolo[1,5-a]pyrimidin-2-yl)-(1-methyl-7-pyridin-2-yl-3,4-dihydro-1H-isoquinolin-2-yl)-methanone | HCID 58416486 | — |
Reaction Steps
In close analogy to the procedure described in Example 1, 6-chloro-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is reacted with 1-Methyl-7-pyridin-2-yl-1,2,3,4-tetrahydro-isoquinoline to provide the title compound in moderate yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07985753B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-14682c096aaa4f03a8698d8ab87d9c28 |
| Source note | uspto-grants-2011_07 |