2,4-Dichlorobenzyl chloride → HCID 25004531, compound

Participants

Reaction Steps

Title compound was prepared via Resin Method using 5-piperazin-1-yl-quinazoline-2,4-diamine (50 mg; 0.2 mmol) and 2,4-Dichlorobenzyl Chloride (72.3 mg; 0.37 mmol) to obtain 48.3 mg. (60% yield). 1H NMR (400 MHz, DMSO-d6) δ 9.71 (s, 1H), 8.49 (s, 1H), 7.60 (m, 3H), 7.44 (m, 1H), 7.16 (m, 2H), 3.66 (s, 2H), 3.02 (br d, J=10.8 Hz, 3H), 2.90 (m, 4H), 2.41 (m, 2H). ESIMS+403.5 m/z

Provenance & Evidence