Benzoyl chloride → HCID 25004872, compound

Participants

Reaction Steps

Title compound was prepared via Resin Method using 5-piperazin-1-yl-quinazoline-2,4-diamine (50 mg; 0.2 mmol) and benzoyl chloride (57.6 mg; 0.41 mmol) to obtain 21.3 mg. (31% yield). 1H NMR (400 MHz, DMSO-d6) δ 8.78 (s, 1H), 7.46 (m, 5H), 7.39 (t, J=6.0 Hz, 1H), 7.14 (br s, 1H), 6.98 (d, J=6.4 Hz, 1H), 6.86 (d, J=5.6 Hz, 1H), 5.92 (br s, 2H), 4.59 (br s, 1H), 3.66 (br s, 1H), 3.44 (m, 1H), 3.13 (m, 3H), 2.77 (m, 2H).

Provenance & Evidence