2,4-Dichlorobenzoyl chloride → HCID 25005213, compound

Participants

Reaction Steps

Title compound was prepared via Resin Method using 5-piperazin-1-yl-quinazoline-2,4-diamine (50 mg; 0.2 mmol) and 2,4-Dichlorobenzoyl chloride (85.9 mg; 0.41 mmol) to obtain 48.1 mg. (58% yield). 1H NMR (400 MHz, DMSO-d6) δ 8.67 (br d, 1H), 7.76 (s, 1H), 7.54 (s, 2H), 7.41 (m, 2H), 7.07 (br d, 1H), 6.98 (br d, 1H), 6.83 (t, J=7.6 Hz, 1H), 4.58 (br d, 1H), 3.42 (m, 2H), 3.16 (m, 2H), 2.99 (m, 1H), 2.74 (m, 2H). ESIMS+419.3 m/z

Provenance & Evidence