HuagongsheHuagongshe Chemistry Print Report · For research reference only
5,5'-Bi-2-benzofuran-1,1',3,3'-tetrone → 3,3',4,4'-Tetra(hydroxymethyl)-1,1'-biphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5,5'-Bi-2-benzofuran-1,1',3,3'-tetrone | HCID 75494 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 3,3',4,4'-Tetra(hydroxymethyl)-1,1'-biphenyl | HCID 59779453 | — |
Reaction Steps
Compound 4 is prepared in two steps from commercially available 3,3′,4,4′-biphenyltetracarboxylic dianhydride as shown in Scheme 4. Dianhydride is reduced with lithium aluminium hydride in dioxane to give 3,3′,4,4′-tetra(hydroxymethyl)-1,1′-biphenyl 3, which is in turn oxidised following a standard swern oxidation procedure to afford tetracarbaldehyde 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07985353B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-b740ec811d494b5cbb35fc0c6bfd471a |
| Source note | uspto-grants-2011_07 |