HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Chlorophenyl)-4-hydroxypiperidine → Benzyl 1-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-3-methyl-1-oxobutan-2-ylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Chlorophenyl)-4-hydroxypiperidine | HCID 38282 | — |
| Reactant | N-Carbobenzoyl-DL-valine | HCID 97743 | — |
| Reactant | 3-Methyl-2-(phenylformamido)butanoic acid | HCID 226682 | — |
| Reactant | 4-(4-chlorophenyl)piperidine Hydrochloride | HCID 2757843 | — |
| Product | Benzyl 1-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-3-methyl-1-oxobutan-2-ylcarbamate | HCID 57888886 | — |
Reaction Steps
Example 213 was prepared in a similar manner as described for the preparation of Example 208 with the exceptions that Cbz-DL-valine and 4-(4-chlorophenyl)-4-hydroxypiperidine were substituted for benzoyl-DL-valine and 4-(4-chlorophenyl)piperidine hydrochloride, respectively. MS found: (M+H)+=446.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07985861B2 |
| Source dataset | uspto-grants-2011_07 |
| ORD ID | ord-9e8f2a3e1fa24d7b85482907f7d8aa2c |
| Source note | uspto-grants-2011_07 |