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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1016231Generated: October 30, 2026

5-(4-Ethoxy-2,3-difluorophenyl)-2-pentylcyclohexanol → 5-(4-Ethoxy-2,3-difluorophenyl)-2-pentyl-cyclohexanone

https://huagongshe.com/reaction/1016231

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Ethoxy-2,3-difluorophenyl)-2-pentylcyclohexanolHCID 11255862—
ReactantHCID 178418287HCID 178418287—
SolventDichloromethaneHCID 6344—
Product5-(4-Ethoxy-2,3-difluorophenyl)-2-pentyl-cyclohexanoneHCID 11438723—

Reaction Steps

48.2 g of 5-(4-ethoxy-2,3-difluorophenyl)-2-pentyl-cyclohexanol were dissolved in 600 ml of dichloromethane, and 30 g of Celite were added. 35.6 g of pyridinium chlorochromate were added with stirring, and the mixture was stirred at RT overnight. Conventional work-up gave 5-(4-ethoxy-2,3-difluorophenyl)-2-pentyl-cyclohexanone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06475595B1
Source datasetuspto-grants-2002_11
ORD IDord-d760383723b140b382716a37a934c9c7
Source noteuspto-grants-2002_11