Piperidine → HCID 18406554, compound

Participants

Reaction Steps

The compound (500 mg) obtained in Example 9 was suspended in ethanol (20 mL) and to the suspension was added piperidine (2 mL). The mixture was heated under reflux for 30 hours under an argon atmosphere and allowed to cool. The solvent was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate =1:1) to obtain the title compound (115 mg; 26%)

Provenance & Evidence