HuagongsheHuagongshe Chemistry Print Report · For research reference only
10-bromo-5-hydroxy-2-(3-pyridylmethyl)-3H-pyrido[3,2,1-kl]phenothiazin-3-one → 5-(5-acetoxymethyl-3-pyridylmethyloxy)-10-bromo-2-(3-pyridylmethyl)-3H-pyrido[3,2,1-kl]phenothiazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 10-bromo-5-hydroxy-2-(3-pyridylmethyl)-3H-pyrido[3,2,1-kl]phenothiazin-3-one | HCID 12021105 | — |
| Reactant | 3-Chloromethyl-5-acetoxymethylpyridine | HCID 18406614 | — |
| Product | 5-(5-acetoxymethyl-3-pyridylmethyloxy)-10-bromo-2-(3-pyridylmethyl)-3H-pyrido[3,2,1-kl]phenothiazin-3-one | HCID 18406581 | 77% |
Reaction Steps
According to Example 34, the compound (250 mg) produced in Example 37 was reacted with 3-chloromethyl-5-acetoxymethylpyridine (175 mg) to obtain the title compound (260 mg; 77%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06476021B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-c0f08de0b8fb4f81acddbc2800eae1b7 |
| Source note | uspto-grants-2002_11 |