HuagongsheHuagongshe Chemistry Print Report · For research reference only
Picolyl chloride hydrochloride → 10-bromo-2-(3-pyridylmethyl)-5-(2-pyridylmethyloxy)-3H-pyrido[3,2,1-kl]phenothiazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Picolyl chloride hydrochloride | HCID 23392 | — |
| Reactant | 10-bromo-5-hydroxy-2-(3-pyridylmethyl)-3H-pyrido[3,2,1-kl]phenothiazin-3-one | HCID 12021105 | — |
| Product | 10-bromo-2-(3-pyridylmethyl)-5-(2-pyridylmethyloxy)-3H-pyrido[3,2,1-kl]phenothiazin-3-one | HCID 12021111 | 67% |
Reaction Steps
According to Example 34, the compound (150 mg) produced in Example 37 was reacted with 2-chloromethylpyridine hydrochloride (84 mg) to obtain the title compound (12 mg; 67%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06476021B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-5b7aee32e4cc410e9b6f1e8d87b6e290 |
| Source note | uspto-grants-2002_11 |