HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloromethylbenzimidazole → 5-(2-benzimidazolylmethyloxy)-10-bromo-2-(3-pyridylmethyl)-3H-pyrido [3,2,1-kl]phenothiazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloromethylbenzimidazole | HCID 78571 | — |
| Reactant | 10-bromo-5-hydroxy-2-(3-pyridylmethyl)-3H-pyrido[3,2,1-kl]phenothiazin-3-one | HCID 12021105 | — |
| Product | 5-(2-benzimidazolylmethyloxy)-10-bromo-2-(3-pyridylmethyl)-3H-pyrido [3,2,1-kl]phenothiazin-3-one | HCID 17798125 | 1.5% |
Reaction Steps
According to Example 34, the compound (500 mg) produced in Example 37 was reacted with 2-chloromethylbenzimidazole (243 mg) to obtain the title compound (10 mg; 0.2%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06476021B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-0347b9f803ba46a781db3b21cce739ed |
| Source note | uspto-grants-2002_11 |