3-Bromo-1-propanol → HCID 12021118, compound

HRID 1016318Notes

Reaction equation

HRID 1016318 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]3[CH:19]=[C:18]([CH2:20][C:21]4[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=4)[C:17](=[O:27])[C:8]4[CH:9]=[C:10]([OH:16])[CH:11]=[C:12]([S:13][C:14]=2[CH:15]=1)[C:7]3=4.Br[CH2:29][CH2:30][CH2:31][OH:32]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]3[CH:19]=[C:18]([CH2:20][C:21]4[CH:22]=[N:23][CH:24]=[CH:25][CH:26]=4)[C:17](=[O:27])[C:8]4[CH:9]=[C:10]([O:16][CH2:29][CH2:30][CH2:31][OH:32])[CH:11]=[C:12]([S:13][C:14]=2[CH:15]=1)[C:7]3=4

Participants

3

Reactant 2

HCID 123083-Bromo-1-propanolHCID 12021117HCID 12021117, compound

Product 1

HCID 12021118HCID 12021118, compoundYield 53%

Procedure

According to Example 34, the compound (120 mg) produced in Example 54 was reacted with 3-bromopropanol (0.04 mL) to obtain the title compound (72 mg; 53%).

Sources & evidence

ORD record
ord-22e25eb9db674e9488ca3324a22a359c
Source dataset
uspto-grants-2002_11
Patent number
US06476021B1

Reaction notes

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