3-(Chloromethyl)pyridine hydrochloride → HCID 17798121, compound

HRID 1016322Notes

Reaction equation

HRID 1016322 reaction equation
[Br:1][C:2]1[CH:15]=[CH:14][C:13]2[S:12][C:11]3[C:6]4=[C:7]([C:17](=[O:20])[CH:18]=[CH:19][N:5]4[C:4]=2[CH:3]=1)[CH:8]=[C:9]([OH:16])[CH:10]=3.Cl.Cl[CH2:23][C:24]1[CH:25]=[N:26][CH:27]=[CH:28][CH:29]=1>>[Br:1][C:2]1[CH:15]=[CH:14][C:13]2[S:12][C:11]3[C:6]4=[C:7]([C:17](=[O:20])[CH:18]=[CH:19][N:5]4[C:4]=2[CH:3]=1)[CH:8]=[C:9]([O:16][CH2:23][C:24]1[CH:25]=[N:26][CH:27]=[CH:28][CH:29]=1)[CH:10]=3

Participants

3

Reactant 2

HCID 233943-(Chloromethyl)pyridine hydrochlorideHCID 18406549HCID 18406549, compound

Product 1

HCID 17798121HCID 17798121, compoundYield 72.2%

Procedure

According to Example 34, the compound (170 mg) produced in Example 58 was reacted with 3-chloromethylpyridine hydrochloride (155 mg) to obtain the title compound (155 mg; 72%).

Sources & evidence

ORD record
ord-62fece82df654c66bd2e7ad6bfd4d149
Source dataset
uspto-grants-2002_11
Patent number
US06476021B1

Reaction notes

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