1-(2-Chloroethyl)piperidine → HCID 17798122, compound

HRID 1016323Notes

Reaction equation

HRID 1016323 reaction equation
[Br:1][C:2]1[CH:15]=[CH:14][C:13]2[S:12][C:11]3[C:6]4=[C:7]([C:17](=[O:20])[CH:18]=[CH:19][N:5]4[C:4]=2[CH:3]=1)[CH:8]=[C:9]([OH:16])[CH:10]=3.Cl[CH2:22][CH2:23][N:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>>[Br:1][C:2]1[CH:15]=[CH:14][C:13]2[S:12][C:11]3[C:6]4=[C:7]([C:17](=[O:20])[CH:18]=[CH:19][N:5]4[C:4]=2[CH:3]=1)[CH:8]=[C:9]([O:16][CH2:22][CH2:23][N:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1)[CH:10]=3

Participants

3

Reactant 2

HCID 748271-(2-Chloroethyl)piperidineHCID 18406549HCID 18406549, compound

Product 1

HCID 17798122HCID 17798122, compoundYield 86.4%

Procedure

According to Example 34, the compound (170 mg) produced in Example 58 was reacted with 1-(2-chloroethyl)piperidine (169 mg) to obtain the title compound (194 mg; 86%).

Sources & evidence

ORD record
ord-cdabff12c2c94f479a852bfa9dcd63a5
Source dataset
uspto-grants-2002_11
Patent number
US06476021B1

Reaction notes

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