3-Bromo-1-propanol → HCID 18406630, compound

HRID 1016326Notes

Reaction equation

HRID 1016326 reaction equation
[CH2:1]([C:8]1[C:9](=[O:27])[C:10]2[CH:11]=[C:12]([OH:26])[CH:13]=[C:14]3[C:23]=2[N:22]([CH:24]=1)[C:21]1[CH:20]=[C:19]([Br:25])[CH:18]=[CH:17][C:16]=1[S:15]3)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Br[CH2:29][CH2:30][CH2:31][OH:32]>>[CH2:1]([C:8]1[C:9](=[O:27])[C:10]2[CH:11]=[C:12]([O:26][CH2:29][CH2:30][CH2:31][OH:32])[CH:13]=[C:14]3[C:23]=2[N:22]([CH:24]=1)[C:21]1[CH:20]=[C:19]([Br:25])[CH:18]=[CH:17][C:16]=1[S:15]3)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 123083-Bromo-1-propanolHCID 18406569HCID 18406569, compound

Product 1

HCID 18406630HCID 18406630, compoundYield 34%

Procedure

According to Example 34, the compound (147 mg) produced in Example 70 was reacted with 3-bromopropanol (42 μl) to obtain the title compound (57 mg; 34%).

Sources & evidence

ORD record
ord-73ad4fae9c1b43728a684e602ab1cc60
Source dataset
uspto-grants-2002_11
Patent number
US06476021B1

Reaction notes

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