HCID 18406553, compound → HCID 18406516, compound

HRID 1016330Notes

Reaction equation

HRID 1016330 reaction equation
[Br:1][C:2]1[CH:15]=[CH:14][C:13]2[S:12][C:11]3[C:6]4=[C:7]([C:17](=[O:27])[C:18]([CH2:20][C:21]5[CH:22]=[N:23][CH:24]=[N:25][CH:26]=5)=[CH:19][N:5]4[C:4]=2[CH:3]=1)[CH:8]=[C:9]([OH:16])[CH:10]=3>BrCCCO>[Br:1][C:2]1[CH:15]=[CH:14][C:13]2[S:12][C:11]3[C:6]4=[C:7]([C:17](=[O:27])[C:18]([CH2:20][C:21]5[CH:22]=[N:23][CH:24]=[N:25][CH:26]=5)=[CH:19][N:5]4[C:4]=2[CH:3]=1)[CH:8]=[C:9]([O:16][CH2:7][CH2:8][CH2:9][OH:16])[CH:10]=3

Participants

3

Reactant 1

HCID 18406553HCID 18406553, compound

Product 1

HCID 18406516HCID 18406516, compoundYield 75.3%

Reagents, catalysts & solvents 1

HCID 123083-Bromo-1-propanolSolvent

Procedure

According to Example 34, the compound (150 mg) produced in Example 76 was reacted with 3-bromopropanol (50 μl) to obtain the title compound (64 mg; 38%).

Sources & evidence

ORD record
ord-dd8968a8f1664d20bd435d83d274a861
Source dataset
uspto-grants-2002_11
Patent number
US06476021B1

Reaction notes

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