4-Fluorobenzohydrazide → HCID 18406877, compound

Participants

Reaction Steps

This compound was prepared using the procedure described in Example 21, steps b) to f), using 3-(2-fluorophenyl)-4-hydroxy-2-furanone (cf. Example 2) instead of 3-tert-butyl-4-hydroxy-2-furanone and 4-fluorobenzoic hydrazide instead of 2,5-difluorobenzoic hydrazide in step e). Data for the title compound: mp=191° C.; 1H NMR (400 MHz, CDCl3) δ 3.92 (3H, s), 5.66 (2H, s), 7.22-7.32 (4H, m), 7.39-7.44 (1H, m), 7.58 (1H, m), 7.90 (1H, s), 8.51-8.55 (2H, m), 9.21 (1H, s); MS (ES+) m/e 420 [MH]+; Anal. Found: C, 60.11; H, 3.52; N, 23.37%. C21H15F2N7O requires: C, 60.14; H, 3.61; N, 23.38%.

Provenance & Evidence