反应详情

This compound was prepared using the procedure described in Example 21, steps b) to f), using 3-(2-fluorophenyl)-4-hydroxy-2-furanone (cf Example 2) instead of 3-tert-butyl-4-hydroxy-2-furanone and 2,6-difluorobenzoic hydrazide instead of 2,5-difluorobenzoic hydrazide in step e). Data for the title compound: mp=163° C.; 1H NMR (360 MHz, CDCl3) δ 3.78 (3H, s), 5.52 (2H, s), 7.16 (2H, m), 7.24-7.29 (2H, m), 7.38-7.44 (1H, m), 7.60-7.65 (2H, m), 7.85 (1H, s), 9.31 (1H, s); MS (ES+) m/e 438 [MH]+.

1. customThis compound was prepared