p-Toluenesulfonic acid → HCID 18186652, compound

Participants

Reaction Steps

A mixture comprised of the tert-butyl 1-cyanomethylcarbamoyl-3-methylbutylcarbamate and anhydrous p-toluenesulfonic acid (3 eq.) in methylene chloride (20 mL) was stirred for approximately 12 hours. The mixture was filtered and the solid material collected was triturated several times with ether to remove excess acid and then dried under vacuum to provide 2-amino-N-cyanomethyl-4-methylpentanamide p-toluenesulfonic acid salt.

Provenance & Evidence