Hydroxyamine hydrochloride → 4-Hydroxyimino-5-methyl-5-phenyl-3-phenylamino-thiazolidine-2-thione

Participants

Reaction Steps

A solution of 4-imino-5-methyl-5-phenyl-3-phenylaminothiazolidine-2-thione (0.31 g) and hydroxylamine hydrochloride (0.16 g) in methanol (15 ml) was refluxed for 6 hrs followed by solvent evaporation. The residue was purified by column chromatography (ethyl acetate-n-hexane, 1/3) to yield 4-hydroxyimino-5-methyl-5-phenyl-3-phenylamino-thiazolidine-2-thione (0.17 g) having a melting point of 83-84° C.

Provenance & Evidence