HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 2-Bromo-1-oxoindan-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1-oxo-2,3-dihydro-1H-indene-5-carbonitrile | HCID 312896 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Bromo-1-oxoindan-5-carbonitrile | HCID 18407238 | — |
Reaction Steps
1-Oxoindane-5-carbonitrile is brominated with bromine in glacial acetic acid with addition of a catalytic amount of 48% strength HBr solution in water and affords 2-bromo-1-oxoindane-5-carbonitrile with a melting point of 115-118° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06476059B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-6e54ad14693d46c5a0dc92736c8e474b |
| Source note | uspto-grants-2002_11 |