Acetone → HCID 9904980, compound

Participants

Reaction Steps

366 mg of 2-chloro-5-pyridin-3-yl-1-indanone are dissolved with 203 mg of N-methylthiourea in 5 ml of methanol and heated to reflux for 7 h. The reaction mixture is cooled and, after addition of 20 ml of acetone, the precipitate is filtered off with suction, washed with acetone and dried in vacuo. Methyl(6-pyridin-3-yl-8H-indeno[1,2-d]thiazol-2-yl)amine hydrochloride is obtained with a melting point of 225° C.

Provenance & Evidence