Peracetic Acid → 1-[3-(Acetyloxy)-2,5,6-trimethoxyphenyl]ethanone

HRID 1016705Notes

Reaction equation

[C:1]([C:4]1[C:5]([O:17][CH3:18])=[C:6]([O:15][CH3:16])[CH:7]=[C:8](C(=O)C)[C:9]=1[O:10][CH3:11])(=[O:3])[CH3:2].[C:19]([O:22]O)(=[O:21])[CH3:20]>>[C:19]([O:22][C:8]1[C:9]([O:10][CH3:11])=[C:4]([C:1](=[O:3])[CH3:2])[C:5]([O:17][CH3:18])=[C:6]([O:15][CH3:16])[CH:7]=1)(=[O:21])[CH3:20]

Participants

Reactant 2

HCID 6585Peracetic Acid

HCID 17821338Ethanone, 1,1′-(2,4,5-trimethoxy-1,3-phenylene)bis-

Product 1

HCID 184077961-[3-(Acetyloxy)-2,5,6-trimethoxyphenyl]ethanoneYield 30%

Procedure

It is moreover known from another class of substances that re action of 3, 5-diacetyl-1,2,4-trimethoxybenzene with peracetic acid provides 5-acetoxy-3acetyl-1,2,4-trimethoxybenzene as byproduct in 30% yield (H.H. Lee et al., J. Chem. Soc. 1965, 2743-2749).

Sources & evidence

ORD record: ord-9967939a4ed44ed8aae7160d0e8a5789
Source dataset: uspto-grants-2002_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06476253B1

Reaction notes

Loading…