HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenepentanoic acid → N-(5Phenylpentanoyl)-L-alanine iso-Butyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenepentanoic acid | HCID 16757 | — |
| Reactant | 2-Methylpropyl (2S)-2-aminopropanoate hydrochloride | HCID 86584981 | — |
| Product | N-(5Phenylpentanoyl)-L-alanine iso-Butyl Ester | HCID 15481770 | — |
Reaction Steps
Following General Procedure B′ and using 5-phenylpentanoic acid (Aldrich) and L-alanine iso-butyl ester hydrochloride (from Example B′ above), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel and purification was by extraction with Et2O followed by washes with aqueous K2CO3 and aqueous HCl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06476263B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-33fa602a649e4d5ca5513b6f8bfa3359 |
| Source note | uspto-grants-2002_11 |