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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1016831Generated: November 1, 2026

(2-Hydroxyphenyl)acetic acid → 2-[(2-Hydroxyphenyl)acetamido]butyric acid isobutyl ester

https://huagongshe.com/reaction/1016831

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Hydroxyphenyl)acetic acidHCID 11970—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-Hydroxyphenyl)acetamido]butyric acid isobutyl esterHCID 53717695—

Reaction Steps

Following General Procedure I′ above and using 2-hydroxyphenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06476263B1
Source datasetuspto-grants-2002_11
ORD IDord-e82ef10f2ec148e19d0c5beaf919f3e5
Source noteuspto-grants-2002_11