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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1016848Generated: October 31, 2026

2-(1-Benzofuran-2-yl)acetic acid → N-[(benzofuran-2-yl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/1016848

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(1-Benzofuran-2-yl)acetic acidHCID 11105888—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(benzofuran-2-yl)acetyl]alanine Iso-butyl EsterHCID 15481779—

Reaction Steps

Following General Procedure I′ above, and using benzofuran-2-ylacetic acid (Maybridge) and alanine iso-butyl ester (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06476263B1
Source datasetuspto-grants-2002_11
ORD IDord-912d6bd5af0c48bdb57001371d5fedd6
Source noteuspto-grants-2002_11