HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Methyl-1,2-oxazol-5-yl)acetic acid → N-[(3-methylisoxazol-5yl)acetyl]alanine Iso-butyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Methyl-1,2-oxazol-5-yl)acetic acid | HCID 4195532 | — |
| Reactant | 2-methylpropyl (2S)-2-aminopropanoate | HCID 13743556 | — |
| Product | N-[(3-methylisoxazol-5yl)acetyl]alanine Iso-butyl Ester | HCID 15481782 | — |
Reaction Steps
Following General Procedure I′ above, and using (3-methyl-isoxazol-5-yl)acetic acid (CAS# 19668-85-0) and alanine iso-butyl ester (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06476263B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-2c1b4c79c5e9450da50ef1696f63d1e6 |
| Source note | uspto-grants-2002_11 |