HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Difluorophenylacetic acid → N-[(2,5-difluorophenyl)acetyl]aIanine iso-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Difluorophenylacetic acid | HCID 522823 | — |
| Reactant | 2-methylpropyl (2S)-2-aminopropanoate | HCID 13743556 | — |
| Product | N-[(2,5-difluorophenyl)acetyl]aIanine iso-butyl ester | HCID 22894969 | — |
Reaction Steps
Following General Procedure I′ above, and using 2,5-difluorophenylacetic acid (Aldrich) and alanine iso-butyl ester (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06476263B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-e5538894e1c94b07872d515c7372fa80 |
| Source note | uspto-grants-2002_11 |