Acetic Anhydride → HCID 18403028, compound

HRID 1017134Notes

Reaction equation

HRID 1017134 reaction equation
[NH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:11]([OH:13])=[O:12])[CH:9]=2)[C:4](=[O:14])[CH2:3][CH2:2]1.[C:15](OC(=O)C)(=[O:17])[CH3:16]>O>[C:15]([N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([C:11]([OH:13])=[O:12])[CH:9]=2)[C:4](=[O:14])[CH2:3][CH2:2]1)(=[O:17])[CH3:16]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 18403025HCID 18403025, compound

Product 1

HCID 18403028HCID 18403028, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

5.0 g of 2,3-dihydro-4-quinolone-7-carboxylic acid and 22.5 g of acetic anhydride were heated to 100° C. for 1 hour. After cooling, water was added and the mixture was extracted with methylene chloride. The organic phase was dried and concentrated.

Workup

  1. temperatureAfter cooling
  2. extractionthe mixture was extracted with methylene chloride
  3. customThe organic phase was dried
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-ade763334d314f79ac1e1800b0803958
Source dataset
uspto-grants-2002_11
Patent number
US06479436B1

Reaction notes

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