2,4-Dimethoxybenzaldehyde → 2-(2,4-dimethoxyphenyl)-3H-quinazolin-4-one

HRID 1017521노트

반응식

HRID 1017521 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[NH:18][C:17](=[O:19])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[N:10]=1.[CH3:20][O:21]C1C=C(OC)C=CC=1C=O>>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:21][CH3:20])[CH:6]=[CH:5][C:4]=1[C:9]1[NH:18][C:17](=[O:19])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[N:10]=1

참가 물질

3

반응물 2

HCID 691752,4-DimethoxybenzaldehydeHCID 1354360052-(2-methoxyphenyl)-3H-quinazolin-4-one

생성물 1

HCID 1354846622-(2,4-dimethoxyphenyl)-3H-quinazolin-4-one수율 84.3%

실험 절차

According to the preparation of 42, 2,4-dimethoxybenzaldehyde (37) (1.2 g, 7.3 mmol) was used to afford 46 (1.7 g, 84.3%) as pale yellow needles.

출처 및 근거

ORD 기록
ord-0063d4a8f07e42228a29b284ee761e84
출처 데이터셋
uspto-grants-2002_11
특허 번호
US06479499B1

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