Veratraldehyde → HCID 135484663, compound

HRID 1017523Notes

Reaction equation

HRID 1017523 reaction equation
COC1C=CC=CC=1C1[NH:18][C:17](=[O:19])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[N:10]=1.[CH3:20][O:21][C:22]1[CH:23]=[C:24]([CH:27]=[CH:28][C:29]=1[O:30][CH3:31])[CH:25]=O>>[CH3:20][O:21][C:22]1[CH:23]=[C:24]([C:25]2[NH:18][C:17](=[O:19])[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[N:10]=2)[CH:27]=[CH:28][C:29]=1[O:30][CH3:31]

Participants

3

Reactant 2

HCID 8419VeratraldehydeHCID 1354360052-(2-methoxyphenyl)-3H-quinazolin-4-one

Product 1

HCID 135484663HCID 135484663, compoundYield 89%

Procedure

According to the preparation of 42, 3,4-dimethoxybenzaldehyde (39) (1.2 g, 7.3 mmol) was used to afford 48 (1.8 g, 89.0%) as pale yellow prism crystals.

Sources & evidence

ORD record
ord-50914413cfc642cfad251e406ad09990
Source dataset
uspto-grants-2002_11
Patent number
US06479499B1

Reaction notes

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