3,5-Dimethoxybenzaldehyde → HCID 135484664, compound

HRID 1017524Notes

Reaction equation

HRID 1017524 reaction equation
COC1C=CC=CC=1C1[NH:18][C:17](=[O:19])[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[N:10]=1.[CH3:20][O:21][C:22]1[CH:23]=[C:24]([CH:27]=[C:28]([O:30][CH3:31])[CH:29]=1)[CH:25]=O>>[CH3:20][O:21][C:22]1[CH:23]=[C:24]([C:25]2[NH:18][C:17](=[O:19])[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[N:10]=2)[CH:27]=[C:28]([O:30][CH3:31])[CH:29]=1

Participants

3

Reactant 2

HCID 817473,5-DimethoxybenzaldehydeHCID 1354360052-(2-methoxyphenyl)-3H-quinazolin-4-one

Product 1

HCID 135484664HCID 135484664, compoundYield 84%

Procedure

According to the preparation of 42, 3,5-dimethoxybenzaldehyde (40) (1.2 g, 7.3 mmol) was used to afford 49 (1.7 g, 84.0%) as pale yellow needles.

Sources & evidence

ORD record
ord-dedf8865394a4479b2a08746e3b36be0
Source dataset
uspto-grants-2002_11
Patent number
US06479499B1

Reaction notes

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