HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxybenzaldehyde → 6-fluoro-2-(3-methoxyphenyl)-3H-quinazolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxybenzaldehyde | HCID 11569 | — |
| Reactant | 2-Amino-5-fluorobenzamide | HCID 10241003 | — |
| Reactant | 2-(2-methoxyphenyl)-3H-quinazolin-4-one | HCID 135436005 | — |
| Product | 6-fluoro-2-(3-methoxyphenyl)-3H-quinazolin-4-one | HCID 135407319 | 46.8% |
Reaction Steps
According to the preparation of compound 42, 3 (1.0 g, 6.5 mmol) and 3-methoxybenzaldehyde (34) (0.9 g, 6.5 mmol) were used to afford 51 (0.8 g, 46.8%) as pale yellow needles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06479499B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-00f05bc189384830b0edeedbaead1e2f |
| Source note | uspto-grants-2002_11 |