HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxybenzaldehyde → 6-(dimethylamino)-2-(3-methoxyphenyl)-3H-quinazolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxybenzaldehyde | HCID 11569 | — |
| Reactant | 2-Amino-5-(dimethylamino)benzamide | HCID 12715797 | — |
| Reactant | 2-(2-methoxyphenyl)-3H-quinazolin-4-one | HCID 135436005 | — |
| Product | 6-(dimethylamino)-2-(3-methoxyphenyl)-3H-quinazolin-4-one | HCID 135471413 | 51.2% |
Reaction Steps
According to the preparation of 42, 25 (1.0 g, 5.6 mmol) and 3-methoxybenzaldehyde (34) (0.8 g, 5.6 mmol) were used to afford 55 (0.8 g, 51.2%) as pale yellow needles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06479499B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-94a3f4c79a3b4e61a68768badea788f7 |
| Source note | uspto-grants-2002_11 |