HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxybenzaldehyde → 2-(3-methoxyphenyl)-6-pyrrolidin-1-yl-3H-quinazolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxybenzaldehyde | HCID 11569 | — |
| Reactant | Benzamide, 2-amino-5-(1-pyrrolidinyl)- | HCID 11264201 | — |
| Reactant | 2-(2-methoxyphenyl)-3H-quinazolin-4-one | HCID 135436005 | — |
| Product | 2-(3-methoxyphenyl)-6-pyrrolidin-1-yl-3H-quinazolin-4-one | HCID 135451572 | 40% |
Reaction Steps
According to the preparation of 42, 26 (1.0 g, 4.9 mmol) and 3-methoxybenzaldehyde (34) (0.7 g, 4.9 mmol) were used to afford 56 (0.6 g, 40.0%) as pale yellow prism crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06479499B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-06211c6c73b247ce8d83b661b4031586 |
| Source note | uspto-grants-2002_11 |