HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxybenzaldehyde → 2-(3-methoxyphenyl)-6-(1-piperidyl)-3H-quinazolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxybenzaldehyde | HCID 11569 | — |
| Reactant | 2-Amino-5-(piperidin-1-yl)benzamide | HCID 10727606 | — |
| Reactant | 2-(2-methoxyphenyl)-3H-quinazolin-4-one | HCID 135436005 | — |
| Product | 2-(3-methoxyphenyl)-6-(1-piperidyl)-3H-quinazolin-4-one | HCID 135467730 | 55% |
Reaction Steps
According to the preparation of 42, 27 (1.0 g, 4.6 mmol) and 3-methoxybenzaldehyde (34) (0.6 g, 4.6 mmol) were used to afford 57 (0.8 g, 55.0%) as pale yellow prism crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06479499B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-4645f5dbcc2746c88ef2dd32bf553d11 |
| Source note | uspto-grants-2002_11 |