HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxybenzaldehyde → 2-(3-methoxyphenyl)-6-(4-methyl-1-piperidyl)-3H-quinazolin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxybenzaldehyde | HCID 11569 | — |
| Reactant | 2-Amino-5-(4-methylpiperidinyl)benzamide | HCID 10728350 | — |
| Reactant | 2-(2-methoxyphenyl)-3H-quinazolin-4-one | HCID 135436005 | — |
| Product | 2-(3-methoxyphenyl)-6-(4-methyl-1-piperidyl)-3H-quinazolin-4-one | HCID 135476137 | 59.9% |
Reaction Steps
According to the preparation of 42, 28 (1.0 g, 4.3 mmol) and 3-methoxybenzaldehyde (34) (0.6 g, 4.3 mmol) were used to afford 58 (0.9 g, 57.6%) as pale yellow prism crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06479499B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-7646fe2849424abbae80ffaefeff5d30 |
| Source note | uspto-grants-2002_11 |