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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1017538Generated: October 31, 2026

Ethyl 4-chlorobutyrate → 4-Ethoxycarbonylpropoxy-2-phenylquinazoline

https://huagongshe.com/reaction/1017538

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-chlorobutyrateHCID 18474—
Reactant4-Methoxy-2-phenylquinazolineHCID 616867—
Product4-Ethoxycarbonylpropoxy-2-phenylquinazolineHCID 7015956388.6%

Reaction Steps

According to the preparation of 69, ethyl 4-chlorobutyrate (1.36 g, 9.00 mmol) was used to yield 72 (1.34 g, 88.6%) as colorless powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06479499B1
Source datasetuspto-grants-2002_11
ORD IDord-61f78afca3474728bae7711c964eea4c
Source noteuspto-grants-2002_11