Ammonium Hydroxide → HCID 12018143, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 3-(1-methylindol-3-yl)-4-[3-(3-azidopropyloxy)phenyl]furan-2,5-dione (1.0 g) in DMF (7 mL) was added and ammonium hydroxide (50 mL). The reaction mixture was heated at 140° C. for 3.5 h, then cooled to room temperature and diluted with water. The precipitates were filtered and dried to give 3-(1-methylindol-3-yl)-4-[3-(3-azidopropyloxy)phenyl]-1H-pyrrole-2,5-dione (0.58 g). MS (EI): M+ 401.

Provenance & Evidence