Morpholine → HCID 18404378, compound

HRID 1017691Notes

Reaction equation

HRID 1017691 reaction equation
[NH:1]1[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[Br:7][CH2:8][C:9]1[C:10]([Cl:20])=[C:11]([S:16](Cl)(=[O:18])=[O:17])[CH:12]=[CH:13][C:14]=1[Cl:15]>>[Br:7][CH2:8][C:9]1[C:10]([Cl:20])=[C:11]([S:16]([N:1]2[CH2:6][CH2:5][O:4][CH2:3][CH2:2]2)(=[O:18])=[O:17])[CH:12]=[CH:13][C:14]=1[Cl:15]

Participants

3

Reactant 2

HCID 8083MorpholineHCID 158190763-(Bromomethyl)-2,4-dichlorobenzene-1-sulfonyl chloride

Product 1

HCID 18404378HCID 18404378, compound

Procedure

Working analogously to Preparation VII, starting from morpholine and 3-bromomethyl-2,4-dichlorobenzenesulphonyl chloride, the expected product is obtained in the form of a yellow solid (Yield=85%) (the product contains the chloromethylated analogue in part).

Sources & evidence

ORD record
ord-5b455808bfd841ecafe516704500de91
Source dataset
uspto-grants-2002_11
Patent number
US06479515B1

Reaction notes

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