3-(3-Benzyl-3H-imidazol-4-yl)-5-methoxy-6,7-dimethylindan-1-one → HCID 178486575、化合物

関与物質

反応手順

3-(3-Benzyl-3H-imidazol-4-yl)-5-methoxy-6,7-dimethylindan-1-one (1.1 g) is dissolved in ethanol (90 ml). The reaction solution is hydrogenated at 50-55° C. with 10% palladium on carbon as catalyst for 7 hours. The mixture is filtered to remove the catalyst, and the filtrate is evaporated under reduced pressure. The product is converted to its hydrochloride salt in ethyl acetate using dry hydrochloric acid. The yield is 0.6 g, m.p. 258-261° C.

情報源と証拠