関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | HCID 178486576 | HCID 178486576 | — |
| 溶媒 | Hydrochloric Acid | HCID 313 | — |
| 生成物 | HCID 178466014 | HCID 178466014 | — |
反応手順
3-(1H-Imidazol4-yl)-5-methoxy-6,7-dimethylindan-1-ol (cis-isomer, 0.1 g) is dissolved in the mixture of ethanol (20 ml) and concentrated hydrochloric acid (2 ml). The solution is stirred at 25° C. for one hour. Work-up of the reaction mixture gives the crude product, which is purified by flash chromatography using methylene chloride-methanol as eluent.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US06479530B2 |
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| 出典データセット | uspto-grants-2002_11 |
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| ORD ID | ord-d72f8add03eb4ce3bfe0b4680de0de97 |
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| 出典メモ | uspto-grants-2002_11 |
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