HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → HCID 88153340, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | HCID 88111420 | HCID 88111420 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 88153340 | HCID 88153340 | — |
Reaction Steps
A solution of 855 mg 3-(SR)-(1-(RS)-(3,5-bis(trifluoromethyl)phenyl)-ethoxy)-2-(RS)-phenylcyclopentane-1-(RS)-carboxylic acid in 20 mL of dry dichloromethane was treated with 2 drops of DMF followed by 0.36 mL of oxalyl chloride. After 1 hour the reaction was evaporated and the residual yellow oil was concentrated twice more from dichloromethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06479518B2 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-5eaf2cded2a3412892789853fe8a31a2 |
| Source note | uspto-grants-2002_11 |