HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic acid, 2-(triphenylphosphoranylidene)-, ethyl ester → HCID 18405063, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic acid, 2-(triphenylphosphoranylidene)-, ethyl ester | HCID 70670 | — |
| Reactant | HCID 18404996 | HCID 18404996 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 18405063 | HCID 18405063 | — |
Reaction Steps
A solution of 1.27 g (4.5 mmol) of N-(4-bromo-2-formyl-benzoyl)-pyrrolidine and 1.65 g (4.5 mmol) of carboethoxymethylene triphenylphosphorane in 45 ml of toluene is heated to 80° C. for 4 hours. After removal of the solvent the residue is purified by flash chromatography (silica gel; methylene chloride/ethanol 99:1 to 99:2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06479524B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-e34a5d66c30143ddbb1770a9e6f176d4 |
| Source note | uspto-grants-2002_11 |