HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroquinone → 2,5-Dimethyl-4-(2-methoxycarbonyl-ethyl-amino)-1-iodo-benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroquinone | HCID 785 | — |
| Reactant | Methyl Acrylate | HCID 7294 | — |
| Reactant | Benzyltrimethylammonium hydroxide | HCID 66854 | — |
| Reactant | (4-Iodo-2,5-Dimethylphenyl)Amine | HCID 4770984 | — |
| Product | 2,5-Dimethyl-4-(2-methoxycarbonyl-ethyl-amino)-1-iodo-benzene | HCID 18405164 | — |
Reaction Steps
15.0 g (0.061 mol) of 2,5-dimethyl-4-iodo-aniline, 55 ml of (0.611 mol) of methyl acrylate, 6 ml of benzyltrimethyl ammonium hydroxide and 0.3 g (3 mmol) of hydroquinone are refluxed for 11 days. Then the excess acrylate is distilled off and the residue is chromatographed on silica gel, eluting with methylene chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06479524B1 |
| Source dataset | uspto-grants-2002_11 |
| ORD ID | ord-65e182c3e64e4a9287ee1088b3c7c16d |
| Source note | uspto-grants-2002_11 |