Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1017825Generated: October 25, 2026

N-(4-hydroxy-2,3,6-trimethylphenyl)formamide → N-[4-[[(E)-3-(4-Isopropylphenyl)-2-propenyl]oxy]-2,3,6-trimethylphenyl]formamide

https://huagongshe.com/reaction/1017825

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(4-hydroxy-2,3,6-trimethylphenyl)formamideHCID 21961295—
Reactant1-[(E)-3-bromo-1-propenyl]-4-isopropylbenzeneHCID 21961313—
SolventEthyl acetate hexaneHCID 21226206—
ProductN-[4-[[(E)-3-(4-Isopropylphenyl)-2-propenyl]oxy]-2,3,6-trimethylphenyl]formamideHCID 2196134259%

Reaction Steps

By using N-(4-hydroxy-2,3,6-trimethylphenyl)formamide and 1-[(E)-3-bromo-1-propenyl]-4-isopropylbenzene, the title compound was synthesized according to Reference Example 17a. Yield: 59%. Melting point: 165-167° C. (Ethyl acetate-hexane).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06479536B1
Source datasetuspto-grants-2002_11
ORD IDord-b6ee3d81ace9491ca948644648c38a27
Source noteuspto-grants-2002_11