2-Bromopyrimidine → HCID 72803448, compound

HRID 101787Notes

Reaction equation

HRID 101787 reaction equation
[Br:33][c:34]1[n:35][cH:36][cH:37][cH:38][n:39]1.[Cl:1][c:2]1[cH:3][c:4]([Cl:5])[cH:6][cH:7][c:8]1-[c:9]1[n:10][c:11]([CH2:12][CH3:13])[c:14]([NH:15][CH:16]2[CH:17]([O:18][CH2:19][CH3:20])[CH2:21][N:22]([c:23]3[s:24][cH:25][cH:26][n:27]3)[CH2:28]2)[n:29][c:30]1[CH2:31][CH3:32].[Cl:40][c:41]1[c:42](-[c:49]2[n:50][c:51]([CH2:66][CH3:67])[c:52]([NH:57][CH:58]3[CH2:59][NH:60][CH2:61][CH:62]3[O:63][CH2:64][CH3:65])[n:53][c:54]2[CH2:55][CH3:56])[cH:43][cH:44][c:45]([O:47][CH3:48])[cH:46]1>>[c:34]1([N:60]2[CH2:59][CH:58]([NH:57][c:52]3[c:51]([CH2:66][CH3:67])[n:50][c:49](-[c:42]4[c:41]([Cl:40])[cH:46][c:45]([O:47][CH3:48])[cH:44][cH:43]4)[c:54]([CH2:55][CH3:56])[n:53]3)[CH:62]([O:63][CH2:64][CH3:65])[CH2:61]2)[n:35][cH:36][cH:37][cH:38][n:39]1

Participants

4

Reactant 3

HCID 783452-BromopyrimidineHCID 22147293HCID 22147293, compoundHCID 731004855-(2,4-dichlorophenyl)-N-[4-ethoxy-1-(1,3-thiazol-2-yl)pyrrolidin-3-yl]-3,6-diethylpyrazin-2-amine

Product 1

HCID 72803448HCID 72803448, compound

Sources & evidence

ORD record
ord-a366d5679b16410eb89ce19b599fc39c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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