反应详情

Dissolve 4-chloro-1-(4-isopropyl-phenyl)-butan-1-one (2.10 g, 9.35 mmol) in carbontetrachloride (30 mL), add N-bromosuccinimide (1.75 g, 9.83 mmol) and benzoylperoxide (3 mg) and stir at reflux for 1 hour. Cool the reaction mixture, filter, wash with water and brine. Dry (MgSO4), filter and vaporate the solvent in vacuo to give the title compound as an amber oil.

1. temperatureat reflux for 1 hour
2. temperatureCool the reaction mixture
3. filtrationfilter
4. washwash with water and brine
5. dry with materialDry (MgSO4)
6. filtrationfilter